“This is the beauty of CLP,” O’Halloran says. “We’re taking blue-sky approaches to bring new insights into cancer and translate those into solutions for patients,” says O’Halloran, the contact principal investigator at CR-PSOC. Silverman’s distinctive U-shape, floor-to-ceiling glass windows and open courtyard allow CLP members to connect and collaborate more easily.Ĭollaboration at CLP led to the creation of the Chicago Region Physical Sciences-Oncology Center (CR-PSOC), a National Cancer Institute-funded coalition of engineers, life scientists and physicists joining forces to better understand cancer and more effectively defeat it. ![]() We all have our own major research questions, but as soon as we start interacting, we find whole new fields of knowledge that can be uncovered.” Tom O’Halloran, Director of Chemistry of Life Processes InstituteĬLP is housed in the Richard and Barbara Silverman Hall for Molecular Therapeutics and Diagnostics, which is designed to increase the physical proximity of these biologists, chemists and engineers to facilitate even greater collaboration. This convergence of expertise is revealing new research questions and opening new areas of inquiry that will have a long-lasting impact on human health. Faculty and students involved in CLP bring together their unique knowledge and skills to transform the diagnosis and treatment of cancer, cardiovascular and kidney disease, infectious diseases, neurodegenerative diseases, and trauma. Located on Northwestern’s Evanston campus, CLP fosters collaborative and transdisciplinary research spanning life science, chemistry, physics, medicine and engineering. Using those drugs alongside conventional chemotherapy significantly improved chemotherapy effectiveness and rendered cancer cells unable to resist treatment. O’Halloran and Backman discovered that drugs that are often used to manipulate sodium and potassium levels in cancer could also be used to change the nuclear structure of cancer cells. ![]() CLP member Backman, whose imaging technology allows an unprecedented look inside cancer cells, was searching for a drug to alter cancer’s nuclear structure. ![]() O’Halloran, founding director of CLP and a world-renowned expert in inorganic chemistry, had previously determined that cancer cells often have a disproportionate balance of sodium and potassium, compared with healthy cells. And without that conversation, they might never have identified existing, FDA-approved drugs that can dramatically improve the effectiveness of cancer treatment. If it weren’t for the transdisciplinary connections created by the Chemistry of Life Processes Institute (CLP), chemist Tom O’Halloran and biomedical engineer Vadim Backman might not have started a casual conversation about their work. CLP is housed in the Richard and Barbara Silverman Hall for Molecular Therapeutics and Diagnostics.
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![]() Agents for management and observability, such as Systems Manager and CloudWatch, are pre-installed on all our macOS AMIs, along with tools such as the AWS Command Line Interface (AWS CLI) and our AWS SDKs. We’ve added a new FAQ section to our documentation to get started with EC2 M1 Mac instances. To see how to launch an EC2 M1 Mac instance from the AWS Management Console or the AWS Command Line Interface (AWS CLI), I invite you to read my last blog post on the subject.ĭuring the six months of the preview, we collected your feedback and fine-tuned the service to your needs. This is 47.8 percent faster than the same set of tasks running on the previous generation of EC2 Mac instances. The new EC2 M1 Mac instances complete this set of tasks in 49 seconds on average. ![]() EC2 M1 Mac instances deliver up to 60 percent better price performance over the x86-based EC2 Mac instances for iPhone and Mac app build workloads.įor example, I tested the time it takes to clean, build, archive, and run the unit tests on a sample project I wrote. Developers building for iPhone, iPad, Apple Watch, and Apple TV will also benefit from faster builds. If you are a Mac developer and re-architecting your apps to natively support Macs with Apple silicon, you may now build and test your apps and take advantage of all the benefits of AWS. The availability of EC2 M1 Mac instances lets you access machines built around the Apple-designed M1 System on Chip (SoC). It connects to your Amazon Virtual Private Cloud (Amazon VPC), boots from Amazon Elastic Block Store (Amazon EBS) volumes, and uses EBS snapshots, Amazon Machine Images (AMIs), security groups and other AWS services such as Amazon CloudWatch and AWS Systems Manager. I have the pleasure of announcing the general availability of EC2 M1 Mac instances.ĮC2 Mac instances are dedicated Mac mini computers attached through Thunderbolt to the AWS Nitro System, which lets the Mac mini appear and behave like another EC2 instance. I know many of you requested access to the preview, and we did our best but could not satisfy everybody. Version 7 is required on Mac OS X 10.14 Mojave or later.Last year, during the re:Invent 2021 conference, I wrote a blog post to announce the preview of EC2 M1 Mac instances. Save hundreds of megabytes, if not gigabytes, of storage on your Mac while protecting your privacy and erasing internet histories. Please contact support and get your feature requests in now! 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Since December 2016, we have worked with our amazing community to update the game almost 40 times, and we now are finalizing a 1.0 version of Astroneer that we are extremely proud of. ![]() A player’s creativity and ingenuity are the key to seeking out and thriving while on exciting planetary adventures!Īstroneer is now nearing the end of Alpha and Early Access development. On this adventure, players can work together to build custom bases above or below ground, create vehicles to explore a vast solar system, and use terrain to create anything they can imagine. Genre: Open World, Survival, Building, Adventure, Sci-fiĮxplore and reshape distant worlds! Astroneer is set during the 25th century’s Intergalactic Age of Discovery, where Astroneers explore the frontiers of outer space, risking their lives in harsh environments to unearth rare discoveries and unlock the mysteries of the universe. ASTRONEER – A game of aerospace industry and interplanetary exploration. 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A drunken college student invites a dance hostess to the big college dance and then forgets he asked her. Watch Mean Girls | Cady Heron is a hit with The Plastics, the A-list girl clique at her new school, until she makes the mistake of falling for Aaron Samuels . Mean Girls tells the story about Lindsay Lohan’s Cady, who is learning to navigate the hierarchy of high school popularity after previously being was 10 years older than her "Mean Girls" character. Mean Girls 2004 PG-13 1 h 37 m IMDb RATING 7. Oh my god Karen, you can’t just ask people why they’re white. 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Is the J&J vaccine safe for those who are pregnant or breastfeeding?ĪCIP also noted that any of the current authorized COVID-19 vaccines, include the J&J vaccine, can be administered to pregnant and breastfeeding women. To date, the J&J vaccine has not been associated with anaphylactic reactions. The most common side effects of the J&J vaccine are similar to those noted in the Pfizer and Moderna vaccines, including pain at the injection site, fatigue, headache, muscle pain and joint pain. What are the risks associated with the J&J vaccine? Importantly, the vaccine was shown to be 85% protective against severe disease, with no differences across countries or across age groups among trial participants. Specifically, in the U.S., the vaccine was 72% protective. The J&J one-dose vaccine was shown to be on average 66% protective against moderate to severe COVID-19 infections overall from 28 days after injection. An adenovirus vector vaccine does not contain any of the components of the SARS-CoV-2 virus that causes COVID-19, so it cannot cause COVID-19. Adenoviruses can be engineered in the laboratory to make them safe and efficient for human use as vaccines by deleting certain sequences that remove their ability to replicate and cause symptomatic infections, making them excellent vectors for delivering vaccine antigens.Ĭan an adenovirus vector vaccine cause COVID-19? This adenovirus vaccine is used as a single intramuscular injection, and when it enters a cell it produces the vaccine protein but cannot replicate inside the cell or cause illness.Īn adenovirus is a part of a family of viruses that cause non-life-threatening infections in the optic, respiratory, or gastrointestinal tissue of a diverse range of hosts, including humans. The vaccine, known as JNJ-78436735 or , is an adenovirus type 26 modified to produce the SARS-CoV-2 Spike protein. Once the adenovirus enters cells, they use that code to make spike proteins. The J&J vaccine uses a harmless adenovirus vector engineered to carry the “genetic code” for the surface spike protein. ![]() The Pfizer and Moderna vaccines are made using messenger RNA, or mRNA, a technology that delivers a bit of “genetic code” to cells to produce the surface spike protein. What is the difference between the Johnson & Johnson (J&J) vaccine, and the Pfizer and Moderna vaccines? Following the recent news regarding this third vaccine, I wanted to share some of the most common questions about Johnson & Johnson’s vaccine. This is the first vaccine currently available that comes in a single dose.Īs a vaccine developer and researcher, I’m incredibly encouraged by the progress made thus far as we continue in our fight against COVID-19. The Centers for Disease Control and Prevention (CDC)’s Advisory Committee on Immunization Practices (ACIP) also endorsed its use in the U.S. 27, the FDA granted emergency use authorization for Johnson & Johnson’s coronavirus vaccine. Now, we have another vaccine in our arsenal. In December 2020, we saw a light at the end of the tunnel as two vaccines – produced by Pfizer and BioNTech and Moderna – were approved by the Food and Drug Administration (FDA) for emergency use in the United States and distribution began. As we begin the month of March, it’s hard to believe COVID-19 has impacted our lives for a full year. ![]() ChatRandom Photo by Chatrandom on App Store Sync messages with and continue conversations where you left off.Ĥ.Filter out connections using #hashtags.Send disappearing videos, photos, and audio messages.In that way, your connection becomes more meaningful and not just a random online experience. 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